John Lilly, the inventor of the isolation tanks and the man who tried to teach languague to dolphins, a brilliant doctor and scientist, completely fucked up his brain on ketamine and LSD. He was doing a long-term experiment on himself. As a result, even when sober he came to think that there is a certain "World control center" staffed by benign ETs who were communicating with him directly. Lilly gave a long interview to the OMNI mag in late 70s - and the interviewer apparently had a hard time to compete with the voices in the Lilly's head. He was not a coherent brilliant scientist anymore, he sounded a lot like a New Age guru.

So you can be my guest and follow Dr. Lilly into the K-hole (may you come back).
But please be aware that there are profound long-term psychologic chances in people who take LSD frquently - they become unworldly and withdrawn. There were people who became permanently psychotic as a result of taking halucinogent. You may not know you are pre-disposed to schizophrenia until the one last trip that gives you the final push.

The brain is a complicated computer with lots of background action we never get to perceive (apart from extreme situations like near-death experience). The brain output - our consciousness - is highly processed, polished product and all what poisioning with halucinogens does is jaming the the process so that lots of weird stuff comes out, the zeros and ones are exposed. You can float out of your body, talk to Gods, re-live your birth, see fascinating patterns or fuzzy alliens. The problem is that all this is not real, it is a just an artifact of some wheels of the mind screeching as they turn in the wrong direction. I can't see how one can get enriched or expanded by chemically produced malfunction. And the brain is not supposed to be used like this, it is quite delicate instrument and even though it can take some abuse and recover one should not expect to be lucky in the Russian Roulette every time. And even if your mind comes back from your trip "enriched" and in one piece, the noise level in your head will never come back down to what it was before, you just wont notice.

I am nor in favor of draconic anti-drug laws (and the brutalizing penal system replete with tracherous and indifferent morons) but I disagree with proponents of drug liberalization. As Theodore Dalrymple pointed out, drug-taking is a vice - an immoral, idiotic and self-defeating way of living and even though the modern society has poor record of inspiring people about meaning of their life, at least the government should not tolerate when people do stupid immoral things like taking drugs to get high.

I think the legallization debate is fundamentally on the wrong track, drug problem is primarily about decadence, about popular culture and bad choices, a symptom of a social decay and even though the governments war on drugs is stupid the enlighted liberal "solutions" are just as bad. The dumb people who are allowed to smoke pot legally are getting a message that it is OK to have a joint every night, pot is not a big deal - and dancing on X-tasy is not a big deal either because everybody now does it there, right. Anythig goes. A man is free and has the right to satisfy any momentary whim he has, regardless of the cost to himself and everybody else.